Giardia lamblia RNA Polymerase II

Giardia lamblia RNA polymerase II: amanitin-resistant transcription.

Giardia lamblia is an early branching eukaryote, and although distinctly eukaryotic in its cell and molecular biology, transcription and translation in G. lamblia demonstrate important differences from these processes in higher eukaryotes. The cyclic octapeptide amanitin is a relatively selective inhibitor of eukaryotic RNA polymerase II (RNAP II) and is commonly used to study RNAP II transcrip...

Giardia Lamblia.

Giardia lamblia Transcriptome Analysis Using TSS-Seq and RNA-Seq

Giardia lamblia is a protozoan parasite that is found worldwide and has both medical and veterinary importance. We applied the transcription start sequence (TSS-seq) and RNA sequence (RNA-seq) techniques to study the transcriptome of the assemblage A WB strain trophozoite. We identified 8000 transcription regions (TR) with significant transcription. Of these regions, 1881 TRs were more than 500...

Giardia lamblia and Giardiasis

Introduction Ask the average outdoors person about Giardia lamblia, and they have certainly heard about it. Almost always, however, they are considerably misinformed about both the organism’s significance in wilderness water and the seriousness of the disease, giardiasis, if contracted. The amount of information easily found on the subject is voluminous. Unfortunately, almost all of it is flawe...

Biology of Giardia lamblia.

Giardia lamblia is a common cause of diarrhea in humans and other mammals throughout the world. It can be distinguished from other Giardia species by light or electron microscopy. The two major genotypes of G. lamblia that infect humans are so different genetically and biologically that they may warrant separate species or subspecies designations. Trophozoites have nuclei and a well-developed c...